Neurodegenerative diseases are debilitating conditions that result in progressive degeneration and / or death of nerve cells. There will be regression of learnt milestones with progressive deterioration of neurologic function with loss of speech, walking, hearing etc. They are rare disorders with many having genetic/metabolic etiology.
Children present with loss of previous milestones, ataxia(gait difficulty), movement disorders , frequent seizures, dementia or cognitive decline. In many cases the baby with neurodegenerative disease may never gain any milestones from very early life.
It is very important to figure look alike treatable diseases which presents with neuroregression. Hence an expert opinion can be the key for correct diagnosis and treatment.